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FAD-dependent urate hydroxylase : ウィキペディア英語版
FAD-dependent urate hydroxylase

FAD-dependent urate hydroxylase (, ''HpxO enzyme'', ''FAD-dependent urate oxidase'', ''urate hydroxylase'') is an enzyme with system name ''urate,NADH:oxygen oxidoreductase (5-hydroxyisourate forming)''.

A non-homologous isofunctional enzyme (NISE) to HpxO was found, and named HpyO. HpyO was determined to be a typical Michaelian enzyme. These FAD-dependent urate hydroxylases are flavoproteins.
This enzyme catalyses the following chemical reaction
: urate + NADH + H+ + O2 \rightleftharpoons 5-hydroxyisourate + NAD+ + H2O
== References ==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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